Hi,
one of the issues that should be addressed in further 2.8 releases is very poor multi-window support of Blender. Currently, the biggest issue is lack of proper window parenting. For example, when you have open multiple Blender instances at once, and one floating window, it is not possible to tell which Blender instance does the floating window belong to on Windows taskbar:
So you may end up working in wrong window, making unintended changes to the wrong scene.